IVF Services

Laser Assisted Hatching

Most people are familiar with the unfortunate fact that most couples who reach the point in an ART cycle when embryos are transferred to the uterus, will not achieve a pregnancy.

One of the most frustrating aspects of assisted reproductive technology for patients and fertility professionals alike has to deal with failure in fertility treatment. This is especially true in couples who have attempted assisted reproductive procedures many times, and also in those whose time is running out because of their age.

It is the published opinion of some IVF scientists that, pregnancy may fail to occur in some cases because of an inability of the embryo to break out or “hatch” from the zona. According to the theory, there are some women who are more prone for this to happen.

To determine if the female partner has problems concerning ovulation, egg transport, fertilization or implantation, various tests may be administered based on the physician’s examination and analysis:

These include women who:

  • Are over 40 years old
  • Have failed to implant in several IVF cycles
  • Have eggs with very thick zona when measured under the microscope
  • Have abnormal hormone profiles indicative of lower quality eggs (elevated FSH levels)

We could assist those embryos in the hatching process. It might be possible to increase the chance of implantation and hence chance of successful pregnancy. And so assisted hatching (AZH) was invented.

Now, a recently developed technique, assisted hatching, is offering new hope to the couples who fall into these categories.

There are many different methods of AZH available. At Blossom Fertility and IVF Centre, we use a laser for AZH – Laser Assisted Hatching.

Assisted hatching is a laboratory technique used with IVF. It involves the use of laser to thin the outer shell (zone pellucida) of the fertilized egg, before the embryo is transferred into the uterus. Assisted hatching is used to enhance the embryos ability to hatch, and also implant, after transfer. The procedure is based on the fact that an alteration in zona pellucida (outer covering of egg) either by drilling a hole through it or by thinning it, will promote hatching or implantation of embryos that are otherwise unable to escape intact from the zona pellucida.

Over recent years lasers have been used increasingly in the in vitro fertilization (IVF) laboratory. The procedures for which lasers are now routinely used include laser assisted hatching or thinning, blastomere biopsy, trophectoderm biopsy and polar body biopsy.

The latest addition to the Assisted Reproductive Technology is the Saturn 5™ Active Laser System. Saturn 5™ Active Laser System is the latest cutting-edge ART technology and is the most advanced, safest and fastest laser system for laser assisted hatching in repeated IVF failures and laser assisted biopsies of embryos for pre-implantation genetic diagnosis in recurrent missed abortions,IVF failures and to detect genetic abnormalities like Thalassemia, Down’s syndrome, Muscular Dystrophy, cystic fibrosis etc in infertile couples’ embryos.

For more information on your previous failed IVF - Assisted Hatching of Embryos Increases IVF Success Rates at Blossom Fertility and IVF Centre, please call on +91 261 2470333 or Email us at info@BlossomBestIVFIndia.com.

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